Runs from the 10 south to San Pedro, continues as CA 110 on Gaffey St. to 9th St. in San Pedro.
I-110 is the same route as SR-110, just a different shield.
The Harbor Freeway is one of the older freeways in Los Angeles. It began in 1954, and was completed in about 1962. Most portions were built with eight lanes, even in the 1950’s. A great deal of the roadway has been reconstructed to include HOV and bus transit stations. The portion from I-10 south to Pacific Coast Highway (SR-1) was signed originally as US 6 and SR-11. In 1963, US 6 was removed and in 1984, SR-11 was renumbered as I-110. Great views of the downtown Los Angeles skyline can be had on clear days.